MySecretFolder has a simple and straightforward user interface, which you may find much easier to use than that of Folder Guard. On the other hand, Folder Guard offers more protection options, giving you more flexibility in protecting your computer resources.
MySecretFolder can protect only one folder at any given time, while Folder Guard lets you protect any number of files and folders at the same time.
MySecretFolder simply hides the secret folder, or assigns a password to it, while Folder Guard lets you fine-tune the access rights to the folder (for example, make it read-only or prevent all access to it, make the folder itself hidden or only its contents, etc.)
MySecretFolder protects the folder in the same way for all users of your computer, while Folder Guard lets you set up the protection so that any particular folder may be protected from some users and accessible to others.
There are many other important features offered by Folder Guard but not supported by MySecretFolder, such as user permissions, trusted modules, file filters, and more.
